Prof.dr. E.R. de Kloet (Ron) Faculty    LUMC, Mathematics & Natural Sciences E-mail    e.kloet@lacdr.leidenuniv.nl Phone    071 527 6210/90     Date of birth August 19, 1944 Place of birth Maarssen Study Chemistry Ph.D. February 22, 1972 Dissertation The distribution of dexamethasone in relation to its effect on pituitary-adrenal activity Date of accession October 1, 1990 Inaugural lecture November 1, 1991 Equilibrium in a changing world Subject Academyprofessorship (KNAW) since 2004

Keywords

Stress, brain, hormones, depression

My inspiration

'Stress is the spice of life' said Hans Selye the father of the stress concept more than half a century ago. And he is right of course: studying the biology of stress touches all aspects of life from health and happiness to disease and misery. The key to the understanding of stress biology is the stress hormone. I want to find out how such hormones can change from protective into harmful signals. What is the cause and what are the consequences? Today such questions are addressed with gene technology to identify vulnerable phenotypes and with indepth analysisof brain functioning under stress to understand why one individual stays healthy and the other gets ill under similar adverse conditions.

Links

http://www.lacdr.nl

http://www.rondekloet.nl

http://www.isihighlycited.com