Lezing
Prof. dr. Andrzej Bartke - The neuro-endocrine regulation of vitality and the life-span
| Datum | donderdag 11 oktober 2012 |
|---|---|
| Tijd | 15:00 – 16:00 uur |
| Faculteit | Geneeskunde/LUMC |
| Locatie | Poortgebouw, LUMC |
With ageing, cellular and tissue damage accumulates, which was thought for a long time to be driven predominantly by chance. In the nineties of the last century genetically determined neuro-endocrine pathways were identified that control the rate of ageing. Professor Bartke was the first to describe their effects in mammals. His work led to major breakthroughs. Contrary to what was commonly believed, mice with reduced growth hormone, insulin and thyroid hormone signalling have increased vitality and lifespan. Being in his seventies now, the research of Professor Bartke is aimed at unravelling the precise mechanisms that enhance vitality in these long living mice.